PDC 423

Toxicology Strategies for Petroleum Industry Exposure Assessments

intermediate | 8 CM Credit Hours / 0.8 CEU/COC / 0.5 CMP
Sunday | 8:00 A.M. – 5:00 P.M.
Limit: 70

Oil and Gas Industry, Toxicology







Petroleum substances are typically complex and variable materials. Their chemical composition is influenced by the raw materials and processing conditions used in the petroleum operations and may include hazardous constituents. Despite their variable composition, petroleum substances also have many similarities. This allows grouping of petroleum substances into “product” groups or categories according to their similarity in physical and chemical properties. This approach has become a useful tool in the hazard characterization of petroleum substances. Proper exposure assessment depends on the chemical hazards present being identified and monitored. Therefore, the ability to recognize the potential chemical hazards present is crucial for worker protection and proper personal protective equipment selection. This PDC will provide the IH professional with the tools necessary to design, implement and conduct exposure assessments of refinery streams and other hazardous chemicals found in the petroleum industry.

Value Added:

Attendees will design and implement an exposure assessment plan for petroleum processes, based on categories and their toxicity, that can be used for worker protection.


Basic experience and knowledge of designing occupational exposure assessments.


Upon completion, the participant will be able to

  • Apply toxicology information to petroleum process categories to develop exposure assessments.
  • Assess which refinery stream component drives the toxicity hence the exposure assessment.
  • Choose when to use the “mixtures” formula for specific petroleum streams.
  • Review different companies approach to adopting occupational exposure limits (OELs) for petroleum streams.
  • Compare which petroleum process stream chemicals are inhalation vs. dermal hazards.
  • Anticipate the reproductive and developmental hazards of petroleum substances.
  • Determine new areas of toxicology research that could potentially influence future OEL-setting.


  • Introduction to Petroleum Operations
  • Overview of Petroleum Operations and Process Streams
  • How to Categorize Streams using Toxicology Data
  • What are the Primary Constituents of Process Streams that drive exposure assessments
  • Selected Hazardous Constituents in Petroleum Substances
    • Benzene
    • H2S
    • Naphthalene
    • Polycyclic Aromatic Hydrocarbons (PAHs)
    • Butadiene
  • Occupational Exposure Limits in the Petroleum Industry
    • How Different Companies Adopt or Set Internally Used Values
    • Lessons Learned from this Process
    • DNELS? How Will they Affect the OEL Process
  • ACGIH® Mixtures Formula – Utility, Its Value and Application to Chemicals found in the Petroleum Industry
    • Overview of the Formula, Its Application and Limitations
    • Examples of its Use with Chemicals in the Petroleum Industry
  • Issues and Applications
  • Inhalation vs. Dermal Exposures
  • Reproductive Issues and New Data
  • Endocrine Disruptors
  • Sharing Toxicology Data Globally
  • Biomonitoring Considerations

Transfer of Knowledge:

Instructors will evaluate participants understanding of the materials presented based on

  • Practice exercises.

Sponsoring Committee: Toxicology, Oil & Gas Working Group

ONLINE COURSE EVALUATION: https://www.surveymonkey.com/s/F6JQGLZ